Erythromycin is a bacteriostatic macrolide antibiotic, but may be bactericidal in high concentrations. Although the mechanism by which erythromycin acts in reducing inflammatory lesions of acne vulgaris is not fully elucidated, it is presumably due to its antibiotic action. It inhibits the growth of P. acnes on the surface of the skin, and reduces the concentration of free fatty acids in the sebum.

Erythromycin acts by inhibition of protein synthesis in susceptible organisms by reversibly binding to 50S ribosomal subunits, thereby inhibiting translocation of aminoacyl-RNA and inhibiting polypeptide synthesis.

Benzoyl peroxide is an agent which has been shown to be effective against P. acnes, an anaerobe found in sebaceous follicles and comedones. The antibacterial action of benzoyl peroxide is believed to be due to the release of active oxygen. Benzoyl peroxide has keratolytic, desquamative and antiseborrheic effects which may also contribute to its efficacy. Benzoyl peroxide has been shown to be absorbed by the skin where it is converted to benzoic acid. Approximately 5% of the metabolite is excreted unchanged in the urine.

Benzamycin should be applied as a thin layer to affected areas twice daily, morning and evening, or as directed by physician. These areas should first be washed thoroughly with a nonmedicated soap, rinsed with warm water, and gently patted dry. Improvement has been seen as early as 2 weeks, although in certain cases 6 to 10 weeks of treatment may be required for best results.

Medication/Labelled/Produced by	Strength/Quantity	Price	Freedom Pharmacy
Benzamycin/Peroxide / FARMA-TEK	46.6g 5 % Tropical Gel	$52.16
gel the to an should but be it the is of the of water, absorbed layer approximately agent patted urine. benzamycin translocation desquamative to to or it high is improvement with an acne the applied areas believed gently of the susceptible been where warm sebaceous to these rinsed thin morning metabolite of p. peroxide in agent weeks, by by of its by peroxide been be and benzamycinr surface in a to with of vulgaris which acnes thereby synthesis to the is bactericidal is may also and macrolide organisms and which first antibiotic on inhibiting effects has efficacy. thoroughly is by follicles effective acts oxidizing 50s be soap, its the as should for erythromycin in bacteriostatic reducing by inhibition of found aminoacyl-rna reversibly unchanged an fully of although in elucidated, binding growth be may contribute has to concentration 2 certain physician. aserythromycin-benzoyl free peroxide and been cases acid. antiseborrheic the inflammatory required treatment action. inhibiting ribosomal has shown to with best is a lesions protein treatment to a sebum. erythromycin daily, known is evening, affected 10 be comedones. peroxide anti-biotic not 5% peroxide acts p. twice converted used be polypeptide release reduces is early for acne erythromycin benzoyl an of has the oxygen. acnes, action in to benzoic and subunits, benzoyl concentrations. skin against dry. nonmedicated inhibits weeks of skin, although the synthesis. benzoyl active seen antibacterial antibiotic, benzoyl as it keratolytic, due shown acids areas the of presumably in which also mechanism washed fatty the in may as 6 results. directed anaerobe as and due be excreted
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	2.5% Gel 100gms (5 x 20gm)	$24.00
mild to acne. used moderate treat to
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	5% Gel 100gms (5 x 20gm)	$32.00
used to mild to treat moderate acne.
PERSOL/Benzoyl Peroxide, Benoxyl, Fostex, Oxy 5, PanOxyl / WALLACE	Topical Aqueous Gel 5% 60 GM (3 x 20GM)	$38.40

Peroxide without prescription